Bextra (valdecoxib) is classified amongst nonsteroidal anti-inflammatory drugs or NSAIDs. Valdecoxib helps to reduce materials in the body that causes tenderness, hurting and high temperature. It also helps to cut down on aches, irritation, and rigidness which is due to osteoarthritis and rheumatoid arthritis in adults.
In addition to the label warnings on Bextra's label of possible side effects of severe skin reactions, a few experiments had a higher risk of indefinite “cardiovascular events” in those patients that had cardiac bypass surgery and who used Bextra.
Bextra (valdecoxib), in addition to the rest of the Prescription nonsteroidal anti-inflammatory drugs (NSAIDs) are one of the leading groups of drugs that cause Stevens Johnson Syndrome (SJS), toxic epidermal necrolysis ( TEN ), and erythema multiforme (EM) due to drug allergy reactions. Possible cardiac troubles that includes strokes and heart attacks are also associated to Bextra.
in October 2004, soon after the FDA took Vioxx, a similar COX -2 inhibitor, off the market due to an higher danger of cardiovascular issues, Pfizer stated that two clinical tests concluded that patients with heart bypass surgery who took Bextra increased their risk of stroke and heart attack.
Possible Bextra Side Effects
- Application site disorders: Cellulitis, dermatitis contact
- Cardiovascular: Irritated hypertension, aneurysm, arrhythmia, anginapectoris, congestive heart failure, cardiomyopathy, coronary artery disorder, hypotension, heart murmur
- Central, peripheral nervous system: Cerebrovascular disorder, hypertonia, hypoesthesia, neuralgia, migraine, neuropathy, pares-thesia, tremor, vertigo, trembling
- Endocrine: Goiter
- Female reproductive: Amenorrhea , dysmenorrhea, leukorrhea, mastitis, menstrual disorder, menorrhagia, vagi-nal hemorrhage, menstrual bloating
- Gastrointestinal: Abnormal stools, constipation, diverticulosis, dry mouth, duodenal ulcer, duodenitis, eructation, esophagitis, fecal incontinence, gastric ulcer, gastritis, gastroe-sophageal reflux, gastroenteritis, hematemesis, hematochezia, hemorrhoids, hem-orrhoids bleeding, hiatal hernia, melena, stomatitis, stool frequency increased, tenesmus, vomiting, tooth disorder
- General: Allergy irritated, allergic response, asthenia, chest pain, chills, cyst NOS, edema generalized, face edema , tiredness, fever, hot flushes, halitosis, malaise, soreness, periorbital puffiness, peripheral pain Hearing and vestibular: Ear irregularity, earache, tinnitus
- Heart rate and rhythm: Bradycardia, tachycardia, palpitation
- Hemic: Anemia
- Liver and biliary system: Hepatic function irregular, hepatitis, ALT increased, AST amplified
- Male reproductive: Impotence , prostatic disorder
- Metabolic and nutritional: Alkaline phosphatase increased, BUN increased, CPK increased, creatinine increased, diabetes mellitus, glycosuria, gout, hypercholesterolemia, hyperglycemia, hyperkalemia, hyperlipemia, hyperuricemia, hypokalemia, LDH increased, more thirsty than normal, weight loss, weight gain, xerophthalmia, hypocalcemia
- Musculoskeletal: Arthralgia, fracture accidental, neck firmness, osteoporosis, synovitis, tendonitis
- Neoplasm: Breast neoplasm, lipoma, malignant ovarian cyst
- Platelets (bleeding or clotting): Ecchymosis, epistaxis, hematoma NOS, thrombocytopenia
- Psychiatric: anxiety , greater appetite, confusion, melancholy , depression aggravated, insomnia, nervousness, morbid dreaming, somnolence, anorexia
- Resistance mechanism disorders: Herpes simplex, herpes zoster, infection fungal, infection soft tissue, infection viral, moniliasis, moniliasis genital, otitis media
- Respiratory: irregular breath sounds, bronchitis, bronchospasm, coughing, dyspnea, emphysema, laryngitis, pneumonia, pharyngitis, pleurisy, rhinitis
- Skin and appendages: Acne , alopecia, dermatitis, dermatitis fun-gal, eczema, photosensitivity allergic reaction, pruritus, rash ery-thematous, rash maculopapular, rash psoriaform, skin dry, skin hypertrophy, skin ulceration, increased sweating, urticaria
- Special senses: Taste distortion
- Urinary system: Albuminuria, cystitis, dysuria, hematuria, micturition frequency increased, pyuria, urinary incontinence, urinary tract infection
- Vascular: Claudication intermittent, hemangioma acquired, varicose vein
- Vision: distorted vision, cataract, conjunctival hemorrhage, con-junctivitis, eye pain, keratitis, irregular vision
- White cell and RES disorders: Eosinophilia, leukopenia, leukocytosis, lymphadenopathy, lymphangitis, lymphopenia
Bextra may have further unrecognized side effects.
Contact Robert J Fenstersheib & Associates right away for a free legal evaluation if you have taken Bextra and are experiencing any of the above listed side effects. Because drug litigation can be very multifaceted, it is best to find the counsel of a personal injury attorney that has the understanding in this field of law. In addition to pharmaceutical and medical product cases, Robert J Fenstersheib & Associates has extensive knowledge with faulty product lawsuits. We will give you personalized, qualified legal representation. |